Luminal A Breast Cancer Co-expression Network: Structural and Functional Alterations
نویسندگان
چکیده
منابع مشابه
Understanding the functional impact of copy number alterations in breast cancer using a network modeling approach.
UNLABELLED Copy number alterations (CNAs) are thought to account for 85% of the variation in gene expression observed among breast tumours. The expression of cis-associated genes is impacted by CNAs occurring at proximal loci of these genes, whereas the expression of trans-associated genes is impacted by CNAs occurring at distal loci. While a majority of these CNA-driven genes responsible for b...
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2021
ISSN: 1664-8021
DOI: 10.3389/fgene.2021.629475